Charges of fake research hit new high

At the time he started cheating, Friedman was in his late 30s, married and a father of two young children. Following the path of his father, grandfather and uncle who were all doctors and medical researchers, he was an associate professor of obstetrics, gynecology and reproductive biology at Harvard Medical School and chief of the department of reproductive endocrinology at Brigham and Women’s Hospital.

His reputation was tremendous and his work groundbreaking. His 30-page resume highlighted numerous awards and honors, lectures in Canada, Europe and Australia, and more than 150 articles, book chapters, reviews and abstracts. Of those, 58 were original research articles, where he had designed studies, conducted clinical trials, enrolled patients, collected and analyzed data and made conclusions.

In the end, investigators found — and Friedman confessed — to making up information for three separate journal articles (one of them never published) involving hormonal treatment of gynecological conditions.

He testified that he was working 80 to 90 hours a week, seeing patients two days a week, doing surgery one day a week, supervising medical residents, serving on as many as 10 different committees at the hospital and the medical school and putting on national medical conferences.

He did seek help, both from a psychiatrist, who counseled him to cut back, and from his boss, who demanded Friedman increase his research and refused to reduce Friedman’s patient load.

As good as Friedman was as a doctor, surgeon and researcher, he was actually a lousy cheater. One thing that brought about his demise, in fact, was that the initials he used for fictitious patients were the same as those of residents and faculty members in his program.

Unlike many scientists who file immediate lawsuits when they’re caught, Friedman was repentant, resigning from his positions at both Brigham and Women’s, and Harvard.

In 1996, Friedman agreed to be excluded for three years from working on federally funded research. During the next three years he consulted with drug companies, he paid a $10,000 fine to the state of Massachusetts and surrendered his medical license for a year, became very active with the American Red Cross, donating more than 500 hours, and attended several lectures on ethics and record-keeping.

“Andy can never undo the damage that his actions have caused. However, he has paid the price — his academic career is ruined, his reputation sullied, and his personal shame unremitting,” wrote Dr. Charles Lockwood, then chair of obstetrics and gynecology at New York University School of Medicine, in a letter on Friedman’s behalf.

In 1999, after successfully petitioning to get his license reinstated, he went to work as director of women’s health care at Ortho-McNeil Pharmaceuticals. The job, which he still has, involves designing and reviewing clinical trials for hormonal birth control, writing package insert labels and lecturing to doctors. Lately he’s appeared on television and in newspaper articles responding to concerns about the safety of the birth control patch.

Mary Anne Wyatt, a retired biochemist in Natick, Mass., is one of several former patients.

“I think it’s not at all surprising that a drug company would hire somebody who is very comfortable with hiding the effects of very dangerous drugs,” said Wyatt, who unsuccessfully sued him.

Ortho-McNeil spokeswoman Bonnie Jacobs said the company was well aware of Friedman’s history when it hired him. “He is an excellent doctor, an asset to our company,” she said.

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