Study back HPV testing for all women over 30

LONDON — New DNA tests looking for the virus responsible for most cases of cervical cancer make sense for all women aged 30 or over, since they can prevent more cases of cancer than smear tests alone, Dutch researchers said on Thursday.

1. Don't miss these Health stories
   1. 

      Robin Pierre
      Nearly 1,000 dogs sick from jerky treats now

      Nearly 1,000 dogs reportedly have been sickened by chicken jerky pet treats from China, according to a new tally of complaints from worried owners submitted to federal veterinary health officials.

   2. No routine PSA tests for men, panel rules
   3. JPMorgan exec's Lyme infection shows need for quick care
   4. Stress turns guys into social butterflies
   5. Toxic mushrooms: Drug promises new cure

Results of a five-year study involving 45,000 women provided the strongest evidence yet in favor of using human papillomavirus (HPV) testing, Chris Meijer and colleagues from the VU University Medical Centre in Amsterdam reported in The Lancet Oncology.

Most cases of infection with the sexually transmitted virus are cleared naturally by the immune system, but persistent infection with certain HPV strains can lead to cervical cancer.

In recent years, tests for these "high-risk" strains have been developed by companies including Roche and Qiagen.

The new tests are known to work well in detecting HPV, but the Dutch study is the first to show they are better than Pap smears alone over two screening rounds set five years apart.

The researchers, who looked at women aged 29 to 56, said use of HPV tests led to earlier detection of pre-cancerous lesions, allowing for treatment that improved protection against cancer.

Hormuzd Katki and Nicolas Wentzensen from the U.S. National Cancer Institute said the results reinforced earlier findings, and provided "overwhelming evidence" of the benefits of including HPV testing in cervical screening programs.