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Video: GOP's top watchdog goes on the attack

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    >>> there are other changes here in washington, like the new chairman of the house committee on oversight and government reform . it's also called the watch dog committee. california republican darrell isa is coming across like, well, an angry watch dog . our report from nbc's andrea mitchell .

    >> reporter: he's a new cop on the beat. the republican's top watch dog , potentially the obama administration's worst nightmare. even before the election, he put president obama on notice, telling rush limbaugh --

    >> he's been one of the most corrupt presidents in modern times .

    >> reporter: today, a very different tone.

    >> i've got a president who inherently wants to get along with me so we can agree on things.

    >> reporter: but he's laid out an ambitious agenda, investigating wikileaks, fannie mae , and the bank bailout. as many as 280 hearings in the first year. and he's already sent more that be 150 letters to industry lobbyists, asking which regulations they would like killed?

    >> they must be extremely happy to have in the chairman of the committee someone who basically says, come on down, show me what you don't like.

    >> reporter: issa 's spokesman says that's no different than president obama holding a summit with industry leaders, or considering a chief of staff with ties to business. but issa also plans to ask officials like tom donilon to testify, reminding veterans of the clinton years of dan burton when he had issa 's job.

    >> i know, but what i can't understand is why you can't give us an answer.

    >> it doesn't matter where the question is political, ridiculous, if there's a subpoena attached to it, you're required by law to produce the documents it asks for.

    >> reporter: the democrats have had the gavel. now the tables are turned.

    >> the biggest pitfall would be if these investigations are perceived as being witch hunts and political in nature as opposed to focused on substance and policy.

    >> reporter: andrea mitchell , nbc news, washington.

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