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updated 7:16 p.m. ET Oct. 15, 2006

LOS ANGELES - Mel Harris, a co-star on the hit 1980s show “thirtysomething,” has filed for divorce from her husband of five years, People magazine reported Saturday.

Harris, 49, cited irreconcilable differences in her petition to divorce investment banker Mike Toomey, filed Oct. 3 in Los Angeles Superior Court, People reported on its Web site. The couple married in 2001.

The couple have no children together, but Harris, who has been married five times, has a 22-year-old son by photographer David Hume Kennerly and a 16-year-old daughter by actor Cotter Smith.

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Harris, who played Hope Murdoch Steadman on “thirtysomething,” was named one of America’s 10 most beautiful women by Harper’s Bazaar in 1989.

In recent years, she has appeared on such TV shows as “Cold Case,” “JAG” and “The West Wing.”