Eating less fat offers little disease protection

updated 1:22 p.m. ET Oct. 16, 2006

CHICAGO - Eating less fat late in life failed to lower the risk of cancer and heart disease among older women, disappointing news for those who expected greater benefits from a healthy diet.

Even so, scientists say the results from the government study of 48,835 women don’t mean dieters should just throw up their hands and eat cake.

Researchers suggested that the women in the long-running study — with an average age of 62 — may have started their healthy eating too late. They also didn’t reduce fats as much as the diet demanded, and most remained overweight, a major risk factor for cancer and heart problems.

“These results do not suggest that people have carte blanche to eat fatty foods without health problems,” said Dr. JoAnn Manson, chief of preventive medicine at Harvard’s Brigham and Women’s Hospital, a co-author of the study and respected nutrition authority.

The eight-year study showed no difference in the rate of breast cancer, colon cancer and heart disease among those who ate lower-fat diets and those who didn’t.

But the scientists declined to call the $415 million venture a failure, pointing to signs of less breast cancer in women who cut out the most fat, and in less heart disease in women who ate low amounts of the worst kinds of fats.

Heart and cancer specialists said the overall results were not surprising since scientific thinking on the role fats play in disease prevention has evolved since this study was designed. That is especially true when it comes to good and bad fats and heart disease.

RELATED LINKS Women’s Health Initiative "Your Guide to a Healthy Heart" National Awareness Campaign for Women About Heart Disease Aim for a Healthy Weight Dietary guidelines for the general public

The research involved postmenopausal women who either cut overall fat consumption and increased vegetables, fruits and grains, or who continued their usual eating habits. The researchers said the dieters may not have cut out enough fat for a meaningful comparison. Cancer and heart disease incidence was similar in both groups.

“The results, of course, are somewhat disappointing. We would have liked this dietary intervention to have a major impact on health,” Manson said.

The study, appearing in Wednesday’s Journal of the American Medical Association, is part of the Women’s Health Initiative, a landmark government project involving tens of thousands of postmenopausal U.S. women. An earlier WHI study linked long-term use of hormone pills with breast cancer and heart disease risks.

HOW TO REDUCE YOUR HEART DISEASE RISK — Don't smoke, and if you do, quit. Women who smoke are two to six times more likely to suffer a heart attack than non-smoking women. — Aim for a healthy weight. It's important for a long, vigorous life. Being overweight and obesity can cause many preventable deaths. — Get moving. Make a commitment to be more physically active. Aim for 30 minutes of moderately intense activity on most, preferably all, days of the week. — Eat for heart health. Choose a diet that is low in saturated fat, trans fat and cholesterol. Be sure to include whole grains, vegetables and fruits. — Know your numbers. Ask your doctor to check your blood pressure, cholesterol (total, HDL, LDL, triglycerides), and blood glucose. Work with your doctor to improve any numbers that are not normal. Source: National Heart Lung and Blood Institute

Low-fat benefits
One of the women in the study, 66-year-old Judy LaCour of Kent, Wash., began the low-fat diet more than 10 years ago.

“I was raised in a farm family where high-fat food was the norm,” LaCour said. “It was a real culture shock for me when I first started.”

But she said she has stuck with the changes and is disease-free. She also thinks the diet has helped keep her weight down while her friends have gotten heavier with age.

The study was designed mainly to investigate breast cancer risk. Dietary fat was initially thought to be implicated because breast cancer rates are high in Western countries with fatty diets, but recent studies have failed to show any relationship, said Dr. Michael Thun of the American Cancer Society.

Recent research also has suggested that for breast cancer in particular, earlier eating habits may have the most influence on risk.

Another target was colon cancer, which some studies have linked with red meat.

Thun said the results aren’t surprising because fat in the diet “is no longer center stage” when it comes to cancer risk. While the Cancer Society recommends limiting fats, that’s primarily because of the calories, Thun said.

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