S. Korea stem-cell researcher quits university

updated 1:11 p.m. ET Dec. 23, 2005

SEOUL, South Korea - South Korean researcher Hwang Woo-suk resigned from his university on Friday after the school said he fabricated stem-cell research that had raised hopes of new cures for hard-to-treat diseases.

A university panel, releasing initial findings of a probe, accused Hwang of damaging the scientific community with his deception, while South Korea’s government rued the scandal surrounding the country’s star scientist and said it may pull its funding for his research.

“I sincerely apologize to the people for creating a shock and disappointment,” Hwang told reporters as he was leaving his office at Seoul National University, considered the country’s top institution of higher learning.

“With an apologetic heart ... I step down as professor,” he said.

However, Hwang still maintained that he had produced the technology to create patient-matched stem cells as he claimed in a May article in the journal Science.

“I emphasize that patient-specific stem cells belong to South Korea and you are going to see this,” said Hwang, a veterinarian.

Earlier Friday, a panel of Seoul National University experts said Hwang had faked results of at least nine of 11 stem cell lines he claimed to have created in the May paper — the first confirmation of allegations that have cast a shadow over all his purported breakthroughs in cloning and stem-cell technology.

“This kind of error is a grave act that damages the foundation of science,” the panel said.

The South Korean government, which had strongly supported Hwang and designated him the country’s first “top scientist,” said Friday it was “miserable” over the reported results of the investigation and will start its own probe over ethics breaches.

Choi Seong-sik, vice minister of science and technology, said it’s impossible to recover money already spent for Hwang, a total $39.9 million for research and facilities since 1998. But his ministry, which admitted errors in its handling of Hwang’s projects, will look at ending other funding and withdraw the “top scientist” designation.

Still, the government said it would support other similar research.

The university panel said Friday it found that “the laboratory data for 11 stem cell lines that were reported in the 2005 paper were all data made using two stem cell lines in total.”

To create fake DNA results purporting to show a match, Hwang’s team split cells from one patient into two test tubes for the analysis — rather than actually match cloned cells to a patient’s original cells, the university said.

“Based on these facts, the data in the 2005 Science paper cannot be some error from a simple mistake, but can only be seen as a deliberate fabrication to make it look like 11 stem-cell lines using results from just two,” the panel said.

“There is no way but that Professor Hwang has been involved,” the university’s dean of research affairs, Roe Jung-hye told a news conference. Hwang “somewhat admits to this,” he added.

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