Bacteria turned into living photographs
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The work, though, isn't intended for commercial markets.
"They aren't going to put Kodak out of business any time soon," said Massachusetts Institute of Technology researcher Drew Endy, a leading synthetic biologist.
Instead, the creation will be used as a sensor to start and stop more complex genetic engineering experiments. The idea is to create a genetically engineered cell that lays dormant until a laser is shined on it, prompting it into action.
Such an accomplishment would add to the growing success of a field that is making strides around the world, in such projects as:
- Scientists in Israel made the world's smallest computer by engineering DNA to carry out mathematical functions.
- J. Craig Venter, the entrepreneurial scientist who mapped the human genome and launched the Rockville, Md.-based research institute named after himself, is attempting to create novel organisms that can produce alternative fuels.
- With a $42.6 million grant that originated at the Bill and Melinda Gates Foundation, Berkeley researchers are engineering the E. coli bug with genes from the wormwood plant and yeast to create a new malaria drug.
Even as they wrestle with scientific hurdles like controlling genetic mutations, thorny ethical issues are cropping up.
It's cheap and easy to buy individual genes online. They cost about $1 each, down from the $18 apiece charged just a few years ago. Researchers last year created a synthetic polio virus by simply stitching together these mail-order genes.
National security experts and even synthetic biologists themselves are concerned that rogue scientists could create new biological weapons — like deadly viruses that lack natural foes. They also worry about innocent mistakes: organisms that could potentially create havoc if allowed to reproduce outside the lab.
Researchers are casting about for ways to self-police the field before it really takes off. Leaders in the field have organized a second national conference to grapple with these issues this coming May and the Arthur P. Sloan Foundation in June handed out a $570,000 grant to study the social implications of the new field.
"This is powerful work and we live in an age that many tools and technologies can be turned into weaponry," said Laurie Zoloth, a bioethicist at Northwestern University. "You always have the problem of dual-use in every new technology. Steel can be used to make sewing needles or spears."
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